The study evaluated the level of mesenchymal stromal progenitor cells and circulating progenitor cells in healthy participants with a BMI less than 30 and in healthy participants with a BMI greater than 30. worked on the association of BMI on progenitor cells in the article, Influence of BMI on Level of Circulating Progenitor Cells. Current research is being done to define the pathophysiology of such conditions. However, there is data showing that an increased BMI may also be protective.Ĭlinicians know that increased BMI influences numerous disease states. These studies show associations between BMI and cancer growth at a cellular level, as well as association with other disease states. Can it have an effect at the cellular level? Literature shows that it does. Įven with these weaknesses, BMI is an excellent tool that is easy to work with, and useful in most patient populations.īMI is a gross measurement of body fat. However, with this normalization, the equation distributes equal mass to each level of height. This does subtract from the utility of BMI in studies that differentiate body types. This was done because the majority of mass remains within the trunk. People with significant lean body mass, for example, could be classified as “overweight” while they would likely have a low body fat percentage. You will see this in bodybuilders and other athletes. In these cases, other anthropometric measurements may offer more clinical relevance.Īnother caveat is that the physical distribution of adipose tissue has been shown in many studies to affect morbidity and mortality. BMI has no way to account for this variable. In the calculation, height is squared to reduce the contribution of leg length in taller people. Since it does not measure adipose tissue, it has the potential for inaccuracy. BMI is considered to be an indication of the relative amount of body fat on an individual's frame. Body mass index has been a useful tool due to its universal acceptance as a categorizing factor of body fatness.
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